By Plane:

(1) Philippine Airlines (once a day) and Cebu Pacific Airlines (Monday, Wednesday, Friday - once a day, Tuesday, Thursday, Saturday, Sunday - twice a day) fly daily to Tuguegarao City departing from Manila. From there you may take a 3-hour bus or van ride to Sta. Ana

(2) Chartered flights may land at the Cagayan North International Airport at Lal-lo, Cagayan. From there you may take a 1 1/2-hour van ride to Sta. Ana 

By Bus:

(1) Florida Bus Line offers daily direct trip to Sta. Ana at three o'clock at their Sampaloc Terminal

(2) Florida Bus Line and Victory Liner offers daily trips to Tuguegarao City. From there you may take a 3-hour bus or van ride to Sta. Ana

(3) Florida Bus line offers daily trips to Gonzaga. From there you may take a 1-hour van ride to Sta. Ana

For Independent Motorists:

(1) Travel north via NLEX, SCTEX and/or TPLEX passing thru Nueva Ecija, Isabela all the way to Cagayan

(2) Travel north via Maharlika Highway passing thru Bulacan, Nueva Ecija, Isabela all the way to Cagayan